What are probiotics?

Your essential guide to our gut heroes

Banner Image
Banner Image

What are probiotics?

"Probiotics are live microorganisms that, when taken in the right amounts, provide health benefits to the body” - World Health Organization (WHO).

Probiotics are live bacteria and yeasts often referred to as "good" or "friendly" bacteria. These microorganisms help restore the natural balance of bacteria in your gut.

Learn about probiotics

This information is intended for educational purposes only and should not be considered medical advice.

Science-based and proven

Our patented bacterial strains have been featured in over 250 clinical studies in 22,000 individuals of all ages.

Beneficial bacteria and gut health

Contrary to the old belief that all bacteria are harmful, we now know that almost all bacteria are either completely harmless, or in fact very beneficial to our health.

Indeed, some bacteria are actually essential for our survival, while only a small fraction poses a potential threat.

Among the “good bacteria,” probiotics may play a crucial role in supporting human health.

What do probiotics do?

Our bodies are home to a mix of trillions of good and bad bacteria. They're pretty much everywhere — the mouth, gut, and skin. Probiotics have been shown to potentially:

  • improve immune system function
  • protect against harmful bacteria
  • improve digestion and absorption of food and nutrients

Under normal or "balanced" conditions, friendly bacteria in the gut outnumber the unfriendly ones. However, the effects of a modern lifestyle (stress, antibiotic use, low-fibre diets) mean a ‘balanced’ state is increasingly hard to obtain.

Maintaining a balanced gut microbiome is crucial for overall well-being, as around 80% of our immune system resides in the gut.

Prebiotics and Probiotics – what's the difference?

Both prebiotics and probiotics support your gut health, but they play different roles.

Prebiotics are commonly fibres that feeds the good bacteria in your gut, helping them to grow and thrive. Think of them as food for your beneficial gut bacteria.

Probiotics, on the other hand, are live bacteria that you can consume through supplements or in low amounts in certain foods, like yogurt and sauerkraut. They add more of these good bacteria to your digestive system.

Together, they help keep your digestive system balanced and healthy.

What are probiotic foods? If I eat fermented foods, do I need a probiotic?

Probiotic foods, such as yogurt, kefir, sauerkraut, kimchi, and other fermented products, contain live bacteria. However, some are processed further which can kill the beneficial microbes. Even if some live microbes persist, their benefits aren’t always proven.

Quality probiotics, in contrast, have guaranteed numbers of live bacteria with established benefits when consumed in sufficient quantities.

So while fermented foods offer a delicious way to introduce gut-friendly sources into your diet, probiotic supplements provide targeted strains with consistent dosages.

Read more about the difference between probiotics and fermented foods

How are probiotics strains named?

Bacteria are classified by genus, species, and strain. Each strain has a unique genetic makeup, resulting in distinct characteristics.

Thus, every strain is different and does different things; each bacterial strain is as unique as you.

That's why just saying "lactic acid bacteria" isn't specific enough. It's important to know the exact strain, like Limosilactobacillus reuteri DSM 17938, to understand what you're getting.

Understanding probiotic strains

Probiotic products may contain one or multiple strains with varying bacteria counts. However, the effectiveness of a probiotic depends on the specific strains it contains. Some strains require a lower amount for efficacy, while others need more.

To be considered a true probiotic, the product needs to contain the same strains and dose used in clinical trials to ensure effectiveness. All BioGaia products fulfil this requirement.

Read more about our probiotic strains

Millions to trillions: Is a bigger CFU count better?

CFU, or "Colony-Forming Units," gives an estimate of how many viable bacteria cells are in each dose, such as a tablet. Although, a higher CFU doesn’t necessarily mean better.

How to read a probiotic label

RECOMMENDED USE: Tells you the intent of the product and what you can expect.

DOSAGE/ USAGE/ SERVING SIZE: The amount that needs to be consumed to obtain the desired effect.

CFU (Colony Forming Units): The number of viable bacteria in the product (sometimes designated as “live cultures”). Avoid products stating CFU “At time of manufacture” - such labelling does not account for decline of CFU during storage. CFU listed is usually a total count, although a count for each strain is desirable. CFU listed on the product label should equal the amount shown to be effective in human studies.

STORAGE INFORMATION: How to store the product to ensure product quality and safety.

COMPANY NAME AND CONTACT INFORMATION: Consumers can contact BioGaia with questions or to get more information.

GENUS, SPECIES, AND STRAIN OF THE BACTERIA: You need all 3 to know what probiotic you are getting. Strain specificity is important as different strains within the same species can have different effects. Choose products that identify down to the strain level.

USE BY/EXPORATION DATE: This will tell you how long the probiotic will contain adequate levels of live probiotics to have the desired effect. Probiotics are living microorganisms, and their numbers can drop off during storage.

How to choose the best probiotic for you?

Selecting a probiotic can be more challenging than picking a multivitamin. The complex names of probiotic strains can be confusing and determining which strain suits your specific needs can be tricky.

When considering a probiotic supplement, it's important to ensure that the strain has been tested in clinical studies to verify its safety and effectiveness, and that the quantity provided is sufficient.

A quality probiotic should also be capable of temporarily colonising the human gut. This colonisation is what helps restore a healthy balance of good and bad bacteria.

All BioGaia products have been clinically proven to reach the gut alive.

International Scientific Association for Probiotics and Prebiotics

As the probiotic industry lacks uniform regulations, particularly regarding efficacy and quality, BioGaia welcomes the International Scientific Association for Probiotics and Prebiotics (ISAPP). ISAPP’s consumer guidelines for making smart choices regarding probiotics.

As proud members of ISAPP, we take pride in offering authentic probiotics, in contrast to other food supplements marketed as such.

Not all products labelled “probiotic” are true probiotics. Here’s how all BioGaia products comply with the International Scientific Association for Probiotics and Prebiotics (ISAPP) guidelines.
Checklist How probiotics by BioGaia comply
It’s backed by science ✓ Products with L. reuteri are among the most scientifically well-documented probiotics in the world.
It provides an effective dose ✓ Through clinical trials on over 22, 000 individuals of varying ages, effective dosing has been verified and varies per product.
It provides the benefit I’m seeking ✓ All BioGaia probiotics are clinically proven to support gut, oral and immune system maintenance.
It’s safe for me ✓ BioGaia strains all have Qualified Presumption of Safety (QPS) status and have undergone rigorous safety assessment, and their use in food is supported by European Food Safety Authority Scientific Panels.
It’s labelled properly ✓ Our labelling always specifies genus, species and strain, shows CFU content at end of shelf-life, specifies recommended dose, specifies storage conditions on the packaging and contact information is visible on all labels.

IS MORE BETTER? Not necessarily. A greater number of colony forming units (CFU) does not always equate a better product. The best known dose is the one that has been tested in humans and shown to provide positive outcomes. These levels can range from 100 million to over a trillion CFU per day depending on the strain.

ARE A GREATER NUMBER OF STRAINS BETTER? It depends on the science. Some studies support the effect of a single-strain probiotic product, while some studies show that specific blends of probiotics strains have a positive outcome. Simply having lots of strains is not a guarantee of a more beneficial product.

DOES STRAIN SPECIFICITY MATTER? Scientists agree that not all probiotics are the same. Choose a strain or strain blend backed by science supporting the function you are looking for.

DO PROBIOTICS HAVE TO ALTER MY MICROBIOTA TO BE EFFECTIVE? Probiotics typically do not take up residence in your gut and may not evoke any detectable change in the microbes that are normally present. As they pass through the gut, probiotics (and the substances they produce) interact with immune cells, our gut cells, dietary components in the gut and the microbes that live in our gut, and that’s how they exert their benefits.

ARE ALL FERMENTED FOODS PROBIOTIC FOODS? Fermented foods are made by live cultures transforming the food. Some are further processed (such as pasteurisation), which can kill the cultures. Even if live microbes remain, they may not provide proven benefits. Probiotics, on the other hand, are live microbes proven to be beneficial in adequate amounts. Fermented foods can be healthy, but they don't always meet the criteria to be called probiotics unless they contain a studied probiotic at a beneficial dose.

*All information according to the International Scientific Association for Probiotics and Prebiotics (ISAPP).

Our experts answer common questions about probiotics!

Bacteria are classified into genus, species and strains. Probiotic strains of the same species have different characteristics, and may therefore have different health effects. For example, clinical studies with the two strains, Limosilactobacillus reuteri (formerly known as Lactobacillus reuteri) ATCC PTA 6475 and Limosilactobacillus reuteri DSM 17938, have shown different effects in clinical studies. That is why a probiotic product must be defined on strain level.

Multi-strain products containing several strains in high doses do not necessarily have a better effect than a single-strain product. Important criteria when choosing a probiotic product are:

The probiotic bacteria must be defined on strain level.
The probiotic product must have been tested in human clinical studies, with the same dose and with the same bacterial strain(s) as in the commercial product.

The patented probiotic strains found in BioGaia's products were originally found to live in the human digestive tract, which means they are very well suited to our bacterial flora. Many other probiotic products on the market contain strains that come from plants or animals.

Even if a bacterium can colonise the gut, regular intake is necessary to maintain sufficiently high levels for proper colonisation. This colonisation is often temporary, which is why taking probiotics daily, whether from food or supplements, is beneficial for ensuring stable levels of probiotics in the gut.

Learn more about probiotics

Fermented foods: What's the difference?

While fermented foods offer a delicious way to introduce gut-friendly sources into our diet, probiotic supplements provide targeted strains with consistent dosages.

Read more
Gut health basics

Your microbiome is a complex and vital part of your overall health, working quietly behind the scenes to keep your body in balance.

Read more
L. reuteri

BioGaia’s probiotic supplements with L. reuteri are among the most extensively studied in the world with over 250 clinical studies.

Read more

Sources

Effects of Probiotics, Prebiotics, and Synbiotics on Human Health - PMC (nih.gov)

Markowiak P and Śliżewska K (2017) Effects of Probiotics, Prebiotics, and Synbiotics on Human Health. Nutrients, 9(9): 1021

Effects of Probiotics, Prebiotics, and Synbiotics on Human Health - PMC (nih.gov)

The benefits of probiotics bacteria - Harvard Health

Probiotics - NHS (nhs.uk)

Probiotic-Checklist-Infographic.pdf (isappscience.org)

Probiotic_labeling-_rev1029-1.pdf (isappscience.org)

Dispelling-Probiotic-Myths.pdf (isappscience.org)

This information is intended for educational purposes only and should not be considered medical advice. The article does not imply that any substance mentioned is intended for the diagnosis, cure, treatment, or prevention of any disease.